Here are the five main regions - all of which you'll want to include in your holiday.
The Delta - the Mississippi River delta is marked by casinos and cotton fields and set to the rhythm of the blues. Visitors can take in a performance at the local juke joint, at a posh casino or at any one of a dozen lively festivals celebrating the Delta's rich musical heritage.
The Capital/River region - stretches from Jackson, Mississippi's capital city and geographic centre, to the historic towns that line the bluffs of the Mississippi River. Jackson is home to exceptional museums, boutique shopping and restaurants representing virtually every culinary style.
The Pines - spans pioneer trails, sacred Native American homelands, and postcard-pretty antebellum towns. Tradition runs deep here, whether it's found in a quaint antique shop, a hallowed Indian mound, a lovingly restored mansion or an old-fashioned country fair.
The Coastal region - coastal Mississippi is a blend of old world elegance and carefree life on the beach. Visitors can hike in thick woodlands, retreat to a quiet artist colony, race down a white-water river, relax on the beach or roll the dice in a glitzy casino, all in a single day. And the area abounds with antique shops and unique specialty stores filled with one-of-a-kind treasures.